General Cell Based Assays
Cambridge Isotope Laboratories GLYCAN-F6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
GLYCAN-F6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL
Waters Corp MassTrak Endocrine Steroid Calibrator Set
The MassTrak Endocrine Steroid Calibrator Set is intended to be used in a clinical biochemistry laboratory by trained professionals for the quantitative determination of steroids (mineralocorticoids, androgens, glucocorticoids and progestogens) in human serum to aid diagnosis of steroid related disorders. The MassTrak Endocrine Steroid Calibrator Set are used to establish a calibration curve which is used to interpolate the steroid concentrations using liquid chromatography – tandem mass spectrometry (LC-MS/MS) systems.The Waters MassTrak Endocrine Steroid Calibrator Set [one box] contains 7 matrix-matched calibrators in human serum and labeling. Contents include:• Calibrator 0 (Cal. 0)• Calibrator 1 (Cal. 1)• Calibrator 2 (Cal. 2)• Calibrator 3 (Cal. 3)• Calibrator 4 (Cal. 4)• Calibrator 5 (Cal. 5)• Calibrator 6 (Cal. 6)
Cayman Chemical DTNB asy Reagent 1ea
An inhibitor of GAC inhibits GAC enzyme activity (EC50 10.64 nM) reduces the viability of A549 NSCLC cells (IC50 4.025 nM) reduces colony formation by and intracellular glutamate levels in A549 cells at 0.1 and 1 UM reduces tumor growth in an A549 mouse xenograft model at 100 mg/kg
Eurofins Discoverx PathHunter eXpress P2RY6 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0500E2CP19M)
The PathHunter P2RY6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. UTP) based activation of P2RY6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY6 and EA-tagged β-Arrestin-2. Activation of P2RY6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress NMBR Total Internalization Assay, 2pl Kit. (93-0939E3CP5M)
The PathHunter NMBR Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of NMBR via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged NMBR and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the NMBR receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Phospho-H2AX (Ser139) Detection Kit, 500 Assay Points
HTRF Human Phospho-H2AX (Ser139) Detection Kit, 500 Assay Points
Abcam Magnesium Assay Kit
Magnesium Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-PLC-γ1 (Tyr783) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-PLC-γ1 (Tyr783) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-HER2 (Tyr1221/1222) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-HER2 (Tyr1221/1222) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-Phospholamban (Ser16) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-Phospholamban (Ser16) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-GSK3α (Ser21) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-GSK3α (Ser21) Detection Kit, 50,000 Assay Points
Cayman Chemical Cel-Based asy Glucose OxId 2mg
An ionizable cationic lipid (pKa 6.5) has been used in the generation of LNPs for the delivery of mRNA and anticancer agents in vivo LNPs containing DMT7 and encapsulating mRNA encoding Il-12 and MSA-2 decrease tumor volume lung metastatic nodule numbers and lung levels of CD4 and CD8 T cells in a 4T1 breast cancer mouse xenograft model of lung metastasis the same LNPs decrease the number of Tregs increase the number of tumor-associated M1 macrophages and increase intratumoral levels of Il-12 Il-2 Tnf-a and Ifn-? in a B16/F10 murine melanoma model
Abcam Acetylcholinesterase Assay Kit (Fluorometric Red)
Acetylcholinesterase Assay Kit (Fluorometric Red)
The product is subject to the following: Abcam Restricted Use Statement